Turmeric is a well-known ancient herbal medicine from the rhizome of Curcuma longa, a member of ginger family, and commonly found in health supplements for knee pain. It possesses remarkable health-promoting properties, thanks to its well-known anti-inflammatory and antioxidant properties, along with many other physiological benefits. Mounting evidence proves the healing properties of turmeric is attributed to its active compounds – curcuminoids.
Curcuminoids are known to suppress inflammation by inhibiting NF-kB, a transcription factor which triggers a cascade of undesirable inflammatory responses in the body. NF-kB is implicated in a host of chronic diseases ranging from cardiovascular diseases to cancer. As a potent antioxidant, curcuminoids effectively to counteract free radicals in two ways: prevention of free radical formation; and quenching of preformed radicals.
Turmeric offers safe and effective therapeutic benefits in alleviating inflammation and pain associated with osteoarthritis and rheumatoid arthritis. Unlike NSAIDs, this natural COX-2 inhibitor does not cause undesirable gastrointestinal side effects. This makes them perfect for joint care supplements to relieve knee pain.
Turmeric extract shows promising results in lowering serum levels of LDL-cholesterol and triglycerides, thus reducing the risk factors for coronary heart diseases.
Many studies have suggested that turmeric helps in managing blood sugar levels. It increases the production of insulin and protects the pancreatic cells from damage caused by oxidative agents.
Curcumin has been shown to prevent the formation and break down amyloid-beta plaques associated with Alzheimer’s disease.
Curcuminoids act by interfering with signalling mechanisms (critical for tumour growth), regulation of apoptosis (cell death), and tumour angiogenesis (new blood vessel formation which feeds tumours).
Curcumin has recently received increased attention in protecting normal tissues from chemotherapy-induced toxicity. It may also enhance the therapeutic efficacy of many anti-cancer drugs and reduce their side effects through pharmacological and pharmacokinetic interactions.
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